Gene Delivery of Cytochrome P450 Epoxygenase Ameliorates Monocrotaline-Induced Pulmonary Artery Hypertension in Rats

Pulmonary arterial hypertension (PAH) is a life-threatening disease that leads to progressive pulmonary hypertension, right heart failure, and death. Endothelial dysfunction and inflammation were implicated in the pathogenesis of PAH. Epoxyeicosatrienoic acids (EETs), products of the cytochrome P450...

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Bibliographic Details
Main Authors: Zheng, Changlong, Wang, Luyun, Li, Rui, Ma, Ben, Tu, Ling, Xu, Xizhen, Dackor, Ryan T., Zeldin, Darryl C., Wang, Dao Wen
Format: Artigo
Language:Inglês
Published: American Thoracic Society 2010
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993093/
https://ncbi.nlm.nih.gov/pubmed/20118222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2009-0161OC
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