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Arachidonic acid cytochrome P450 epoxygenase pathway
Cytochrome P450 (CYP) epoxygenases convert arachidonic acid to four epoxyeicosatrienoic acid (EET) regioisomers, 5,6-, 8,9-, 11,12-, and 14,15-EET, that function as autacrine and paracrine mediators. EETs produce vascular relaxation by activating smooth muscle large-conductance Ca(2+)-activated K(+)...
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| Hlavní autor: | |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Biochemistry and Molecular Biology
2009
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2674692/ https://ncbi.nlm.nih.gov/pubmed/18952572 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.R800038-JLR200 |
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