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Roles of the epoxygenase CYP2J2 in the endothelium

Cytochrome p450 (CYP)2J2 is an epoxygenase enzyme that metabolises arachidonic acid to epoxyeicosatrienoic acids (EETs). EETs are inactivated by soluble epoxide hydrolase (sEH), which converts them in to their corresponding dihydroxyeicosatrienoic acids (DHETs). CYP2J2 is highly expressed in cardiov...

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Bibliografiska uppgifter
Huvudupphovsmän: Askari, Ara, Thomson, Scott J., Edin, Matthew L., Zeldin, Darryl C., Bishop-Bailey, David
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2013
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3711961/
https://ncbi.nlm.nih.gov/pubmed/23474289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.prostaglandins.2013.02.003
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