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Cyp2j5-Gene Deletion Affects on Acetylcholine and Adenosine-Induced Relaxation in Mice: Role of Angiotensin-II and CYP-Epoxygenase Inhibitor

Previously, we showed vascular endothelial overexpression of human-CYP2J2 enhances coronary reactive hyperemia in Tie2-CYP2J2 Tr mice, and eNOS(−/−) mice had overexpression of CYP2J-epoxygenase with adenosine A(2A) receptor-induced enhance relaxation, but we did not see the response in CYP2J-epoxyge...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Agba, Stephanie, Hanif, Ahmad, Edin, Matthew L., Zeldin, Darryl C., Nayeem, Mohammed A.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7014568/
https://ncbi.nlm.nih.gov/pubmed/32116704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00027
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