Adenosine A(2A) receptor modulates vascular response in soluble epoxide hydrolase-null mice through CYP-epoxygenases and PPARγ

The interaction between adenosine and soluble epoxide hydrolase (sEH) in vascular response is not known. Therefore, we hypothesized that lack of sEH in mice enhances adenosine-induced relaxation through A(2A) adenosine receptors (AR) via CYP-epoxygenases and peroxisome proliferator-activated recepto...

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Détails bibliographiques
Auteurs principaux: Nayeem, Mohammed A., Pradhan, Isha, Mustafa, S. Jamal, Morisseau, Christophe, Falck, John R., Zeldin, Darryl C.
Format: Artigo
Langue:Inglês
Publié: American Physiological Society 2013
Sujets:
Cardiovascular and Renal Integration
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3543649/
https://ncbi.nlm.nih.gov/pubmed/23152114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00213.2012
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