Modulation by salt intake of the vascular response mediated through adenosine A(2A) receptor: role of CYP epoxygenase and soluble epoxide hydrolase

High-salt intake can change the effect of adenosine on arterial tone in mice. The aim of this study was to clarify the mechanism by which this occurs. Using aortas from mice fed a 4% NaCl (HS) or 0.45% NaCl (NS) diet for 4–5 wks, concentration-response curves for ACh, 5′-N-ethylcarboxamidoadenosine...

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Autors principals: Nayeem, Mohammed A., Zeldin, Darryl C., Boegehold, Matthew A., Morisseau, Christophe, Marowsky, Anne, Ponnoth, Dovenia S., Roush, Kevin P., Falck, John R.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2010
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904154/
https://ncbi.nlm.nih.gov/pubmed/20427718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00823.2009
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