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Reduced Coronary Reactive Hyperemia in Mice was Reversed by the Soluble Epoxide Hydrolase Inhibitor (t-AUCB): Role of Adenosine A(2A) Receptor and Plasma Oxylipins
Coronary reactive hyperemia (CRH) protects the heart against ischemia. Adenosine A(2A)AR– deficient (A(2A)AR(−/−)) mice have increased expression of soluble epoxide hydrolase (sEH); the enzyme responsible for breaking down the cardioprotective epoxyeicosatrienoic acids (EETs) to dihydroxyeicosatrien...
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| Опубликовано в: : | Prostaglandins Other Lipid Mediat |
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| Главные авторы: | , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5635996/ https://ncbi.nlm.nih.gov/pubmed/28890385 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.prostaglandins.2017.09.001 |
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