Reduced Coronary Reactive Hyperemia in Mice was Reversed by the Soluble Epoxide Hydrolase Inhibitor (t-AUCB): Role of Adenosine A(2A) Receptor and Plasma Oxylipins

Coronary reactive hyperemia (CRH) protects the heart against ischemia. Adenosine A(2A)AR– deficient (A(2A)AR(−/−)) mice have increased expression of soluble epoxide hydrolase (sEH); the enzyme responsible for breaking down the cardioprotective epoxyeicosatrienoic acids (EETs) to dihydroxyeicosatrien...

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Publicado no:Prostaglandins Other Lipid Mediat
Main Authors: Hanif, Ahmad, Edin, Matthew L., Zeldin, Darryl C., Morisseau, Christophe, Falck, John R., Ledent, Catherine, Tilley, Stephen L., Nayeem, Mohammed A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5635996/
https://ncbi.nlm.nih.gov/pubmed/28890385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.prostaglandins.2017.09.001
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