Ecto-5′-Nucleotidase (CD73) Regulates the Survival of CD8+ T Cells

Ecto-5′-nucleotidase (CD73) is an enzyme present on the surface of tumor cells whose primary described function is the production of extracellular adenosine. Due to the immunosuppressive properties of adenosine, CD73 is being investigated as a target for new antitumor therapies. We and others have d...

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發表在:Front Cell Dev Biol
Main Authors: Rosemblatt, Mariana V., Parra-Tello, Brian, Briceño, Pedro, Rivas-Yáñez, Elizabeth, Tucer, Suat, Saavedra-Almarza, Juan, Hörmann, Pilar, Martínez, Brandon A., Lladser, Álvaro, Rosemblatt, Mario, Cekic, Caglar, Bono, María Rosa, Sauma, Daniela
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2021
主題:
Cell and Developmental Biology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC8076893/
https://ncbi.nlm.nih.gov/pubmed/33928082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.647058
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