Ecto-5′-Nucleotidase (CD73) Regulates the Survival of CD8+ T Cells

Ecto-5′-nucleotidase (CD73) is an enzyme present on the surface of tumor cells whose primary described function is the production of extracellular adenosine. Due to the immunosuppressive properties of adenosine, CD73 is being investigated as a target for new antitumor therapies. We and others have d...

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Veröffentlicht in:Front Cell Dev Biol
Hauptverfasser: Rosemblatt, Mariana V., Parra-Tello, Brian, Briceño, Pedro, Rivas-Yáñez, Elizabeth, Tucer, Suat, Saavedra-Almarza, Juan, Hörmann, Pilar, Martínez, Brandon A., Lladser, Álvaro, Rosemblatt, Mario, Cekic, Caglar, Bono, María Rosa, Sauma, Daniela
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
Schlagworte:
Cell and Developmental Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8076893/
https://ncbi.nlm.nih.gov/pubmed/33928082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.647058
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