Ecto-5′-Nucleotidase (CD73) Regulates the Survival of CD8+ T Cells

Ecto-5′-nucleotidase (CD73) is an enzyme present on the surface of tumor cells whose primary described function is the production of extracellular adenosine. Due to the immunosuppressive properties of adenosine, CD73 is being investigated as a target for new antitumor therapies. We and others have d...

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Foilsithe in:Front Cell Dev Biol
Main Authors: Rosemblatt, Mariana V., Parra-Tello, Brian, Briceño, Pedro, Rivas-Yáñez, Elizabeth, Tucer, Suat, Saavedra-Almarza, Juan, Hörmann, Pilar, Martínez, Brandon A., Lladser, Álvaro, Rosemblatt, Mario, Cekic, Caglar, Bono, María Rosa, Sauma, Daniela
Formáid: Artigo
Teanga:Inglês
Foilsithe: Frontiers Media S.A. 2021
Ábhair:
Cell and Developmental Biology
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8076893/
https://ncbi.nlm.nih.gov/pubmed/33928082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.647058
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