Ecto-5′-Nucleotidase (CD73) Regulates the Survival of CD8+ T Cells

Ecto-5′-nucleotidase (CD73) is an enzyme present on the surface of tumor cells whose primary described function is the production of extracellular adenosine. Due to the immunosuppressive properties of adenosine, CD73 is being investigated as a target for new antitumor therapies. We and others have d...

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Опубликовано в: :Front Cell Dev Biol
Главные авторы: Rosemblatt, Mariana V., Parra-Tello, Brian, Briceño, Pedro, Rivas-Yáñez, Elizabeth, Tucer, Suat, Saavedra-Almarza, Juan, Hörmann, Pilar, Martínez, Brandon A., Lladser, Álvaro, Rosemblatt, Mario, Cekic, Caglar, Bono, María Rosa, Sauma, Daniela
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2021
Предметы:
Cell and Developmental Biology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8076893/
https://ncbi.nlm.nih.gov/pubmed/33928082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.647058
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