Ecto-5′-nucleotidase (CD73) regulation by hypoxia-inducible factor-1 mediates permeability changes in intestinal epithelia

Under conditions of limited oxygen availability (hypoxia), multiple cell types release adenine nucleotides in the form of ATP, ADP, and AMP. Extracellular AMP is metabolized to adenosine by surface-expressed ecto-5′-nucleotidase (CD73) and subsequently activates surface adenosine receptors regulatin...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Synnestvedt, Kristin, Furuta, Glenn T., Comerford, Katrina M., Louis, Nancy, Karhausen, Jorn, Eltzschig, Holger K., Hansen, Karl R., Thompson, Linda F., Colgan, Sean P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2002
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC151145/
https://ncbi.nlm.nih.gov/pubmed/12370277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI15337
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados