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Hypoxia-Inducible Factor-1α–Dependent Protection from Intestinal Ischemia/Reperfusion Injury Involves Ecto-5′-Nucleotidase (CD73) and the A2B Adenosine Receptor

Intestinal ischemia/reperfusion injury (IR) is characterized by intermittent loss of perfusion to the gut, resulting in dramatic increases in morbidity and mortality. Based on previous studies indicating an anti-inflammatory role for hypoxia-inducible factor (HIF)-1–elicited enhancement of extracell...

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Detalhes bibliográficos
Main Authors: Hart, Melanie L., Grenz, Almut, Gorzolla, Iris C., Schittenhelm, Jens, Dalton, Julee H., Eltzschig, Holger K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3884622/
https://ncbi.nlm.nih.gov/pubmed/21357264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0903617
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