Epithelial HIF-1α/claudin-1 axis regulates barrier dysfunction in eosinophilic esophagitis

Epithelial barrier dysfunction is a significant factor in many allergic diseases, including eosinophilic esophagitis (EoE). Infiltrating leukocytes and tissue adaptations increase metabolic demands and decrease oxygen availability at barrier surfaces. Understanding of how these processes impact barr...

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Dades bibliogràfiques
Publicat a:J Clin Invest
Autors principals: Masterson, Joanne C., Biette, Kathryn A., Hammer, Juliet A., Nguyen, Nathalie, Capocelli, Kelley E., Saeedi, Bejan J., Harris, Rachel F., Fernando, Shahan D., Hosford, Lindsay B., Kelly, Caleb J., Campbell, Eric L., Ehrentraut, Stefan F., Ahmed, Faria N., Nakagawa, Hiroshi, Lee, James J., McNamee, Eóin N., Glover, Louise E., Colgan, Sean P., Furuta, Glenn T.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6668670/
https://ncbi.nlm.nih.gov/pubmed/31264974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI126744
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