Influence of Activin A Supplementation During Human Embryonic Stem Cell Derivation on Germ Cell Differentiation Potential

Human embryonic stem cells (hESCs) are more similar to “primed” mouse epiblast stem cells (mEpiSCs). mEpiSCs, which are derived in Activin A, show an increased propensity to form primordial germ cell (PGC)-like cells in response to bone morphogenic protein 4 (BMP4). Hence, we hypothesized that hESCs...

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Detaylı Bibliyografya
Asıl Yazarlar: Duggal, Galbha, Heindryckx, Björn, Warrier, Sharat, O'Leary, Thomas, Van der Jeught, Margot, Lierman, Sylvie, Vossaert, Liesbeth, Deroo, Tom, Deforce, Dieter, Chuva de Sousa Lopes, Susana M., De Sutter, Petra
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Mary Ann Liebert, Inc. 2013
Konular:
Original Research Reports
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3856713/
https://ncbi.nlm.nih.gov/pubmed/23829223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2013.0024
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