Inhibition of Transforming Growth Factor β Signaling Promotes Epiblast Formation in Mouse Embryos

Early lineage segregation in preimplantation embryos and maintenance of pluripotency in embryonic stem cells (ESCs) are both regulated by specific signaling pathways. Small molecules have been shown to modulate these signaling pathways. We examined the influence of several small molecules and growth...

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Veröffentlicht in:Stem Cells Dev
Hauptverfasser: Ghimire, Sabitri, Heindryckx, Björn, Van der Jeught, Margot, Neupane, Jitesh, O'Leary, Thomas, Lierman, Sylvie, De Vos, Winnok H., Chuva de Sousa Lopes, Susana, Deroo, Tom, De Sutter, Petra
Format: Artigo
Sprache:Inglês
Veröffentlicht: Mary Ann Liebert, Inc. 2015
Schlagworte:
Original Research Reports
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4313423/
https://ncbi.nlm.nih.gov/pubmed/25245024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2014.0206
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