Inhibition of Transforming Growth Factor β Signaling Promotes Epiblast Formation in Mouse Embryos

Early lineage segregation in preimplantation embryos and maintenance of pluripotency in embryonic stem cells (ESCs) are both regulated by specific signaling pathways. Small molecules have been shown to modulate these signaling pathways. We examined the influence of several small molecules and growth...

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Detalhes bibliográficos
Publicado no:Stem Cells Dev
Main Authors: Ghimire, Sabitri, Heindryckx, Björn, Van der Jeught, Margot, Neupane, Jitesh, O'Leary, Thomas, Lierman, Sylvie, De Vos, Winnok H., Chuva de Sousa Lopes, Susana, Deroo, Tom, De Sutter, Petra
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2015
Assuntos:
Original Research Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4313423/
https://ncbi.nlm.nih.gov/pubmed/25245024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2014.0206
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