Influence of Activin A Supplementation During Human Embryonic Stem Cell Derivation on Germ Cell Differentiation Potential

Human embryonic stem cells (hESCs) are more similar to “primed” mouse epiblast stem cells (mEpiSCs). mEpiSCs, which are derived in Activin A, show an increased propensity to form primordial germ cell (PGC)-like cells in response to bone morphogenic protein 4 (BMP4). Hence, we hypothesized that hESCs...

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Hlavní autoři: Duggal, Galbha, Heindryckx, Björn, Warrier, Sharat, O'Leary, Thomas, Van der Jeught, Margot, Lierman, Sylvie, Vossaert, Liesbeth, Deroo, Tom, Deforce, Dieter, Chuva de Sousa Lopes, Susana M., De Sutter, Petra
Médium: Artigo
Jazyk:Inglês
Vydáno: Mary Ann Liebert, Inc. 2013
Témata:
Original Research Reports
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3856713/
https://ncbi.nlm.nih.gov/pubmed/23829223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2013.0024
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