Activin A‐derived human embryonic stem cells show increased competence to differentiate into primordial germ cell‐like cells

Protocols for specifying human primordial germ cell‐like cells (hPGCLCs) from human embryonic stem cells (hESCs) remain hindered by differences between hESC lines, their derivation methods, and maintenance culture conditions. This poses significant challenges for establishing reproducible in vitro m...

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Detalhes bibliográficos
Publicado no:Stem Cells
Main Authors: Mishra, Swati, Taelman, Jasin, Popovic, Mina, Tilleman, Laurentijn, Duthoo, Evi, van der Jeught, Margot, Deforce, Dieter, van Nieuwerburgh, Filip, Menten, Björn, de Sutter, Petra, Boel, Annekatrien, Chuva De Sousa Lopes, Susana M., Heindryckx, Björn
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2021
Assuntos:
Embryonic Stem Cells/Induced Pluripotent Stem Cells
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8248136/
https://ncbi.nlm.nih.gov/pubmed/33470497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.3335
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