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Activin A‐derived human embryonic stem cells show increased competence to differentiate into primordial germ cell‐like cells

Protocols for specifying human primordial germ cell‐like cells (hPGCLCs) from human embryonic stem cells (hESCs) remain hindered by differences between hESC lines, their derivation methods, and maintenance culture conditions. This poses significant challenges for establishing reproducible in vitro m...

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Vydáno v:Stem Cells
Hlavní autoři: Mishra, Swati, Taelman, Jasin, Popovic, Mina, Tilleman, Laurentijn, Duthoo, Evi, van der Jeught, Margot, Deforce, Dieter, van Nieuwerburgh, Filip, Menten, Björn, de Sutter, Petra, Boel, Annekatrien, Chuva De Sousa Lopes, Susana M., Heindryckx, Björn
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley & Sons, Inc. 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8248136/
https://ncbi.nlm.nih.gov/pubmed/33470497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.3335
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