Activin A‐derived human embryonic stem cells show increased competence to differentiate into primordial germ cell‐like cells

Protocols for specifying human primordial germ cell‐like cells (hPGCLCs) from human embryonic stem cells (hESCs) remain hindered by differences between hESC lines, their derivation methods, and maintenance culture conditions. This poses significant challenges for establishing reproducible in vitro m...

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Veröffentlicht in:Stem Cells
Hauptverfasser: Mishra, Swati, Taelman, Jasin, Popovic, Mina, Tilleman, Laurentijn, Duthoo, Evi, van der Jeught, Margot, Deforce, Dieter, van Nieuwerburgh, Filip, Menten, Björn, de Sutter, Petra, Boel, Annekatrien, Chuva De Sousa Lopes, Susana M., Heindryckx, Björn
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley & Sons, Inc. 2021
Schlagworte:
Embryonic Stem Cells/Induced Pluripotent Stem Cells
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8248136/
https://ncbi.nlm.nih.gov/pubmed/33470497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.3335
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