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Remarkable Stabilization of Plasminogen Activator Inhibitor 1 in a “Molecular Sandwich” Complex

Plasminogen activator inhibitor 1 (PAI-1) levels are elevated in a number of life threatening conditions and often correlate with unfavorable outcomes. Spontaneous inactivation due to active to latent transition limits PAI-1 activity in vivo. While endogenous vitronectin (Vn) stabilizes PAI-1 by 1.5...

詳細記述

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書誌詳細
主要な著者: Florova, Galina, Karandashova, Sophia, Declerck, Paul J., Idell, Steven, Komissarov, Andrey A.
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3855604/
https://ncbi.nlm.nih.gov/pubmed/23734661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi400470s
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