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Effects of Extracellular DNA on Plasminogen Activation and Fibrinolysis

The increased levels of extracellular DNA found in a number of disorders involving dysregulation of the fibrinolytic system may affect interactions between fibrinolytic enzymes and inhibitors. Double-stranded (ds) DNA and oligonucleotides bind tissue-(tPA) and urokinase (uPA)-type plasminogen activa...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Komissarov, Andrey A., Florova, Galina, Idell, Steven
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3234961/
https://ncbi.nlm.nih.gov/pubmed/21976662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.301218
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