Organizing empyema induced in mice by Streptococcus pneumoniae: effects of plasminogen activator inhibitor-1 deficiency

BACKGROUND: Pleural infection affects about 65,000 patients annually in the US and UK. In this and other forms of pleural injury, mesothelial cells (PMCs) undergo a process called mesothelial (Meso) mesenchymal transition (MT), by which PMCs acquire a profibrogenic phenotype with increased expressio...

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Detalhes bibliográficos
Publicado no:Clin Transl Med
Main Authors: Tucker, Torry A., Jeffers, Ann, Boren, Jake, Quaid, Brandon, Owens, Shuzi, Koenig, Kathleen B., Tsukasaki, Yoshikazu, Florova, Galina, Komissarov, Andrey A., Ikebe, Mitsuo, Idell, Steven
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2016
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Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4896893/
https://ncbi.nlm.nih.gov/pubmed/27271877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40169-016-0097-2
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