KIF5A transports collagen vesicles of myofibroblasts during pleural fibrosis

Fibrosis involves the production of extracellular matrix proteins in tissues and is often preceded by injury or trauma. In pleural fibrosis excess collagen deposition results in pleural thickening, increased stiffness and impaired lung function. Myofibroblasts are responsible for increased collagen...

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Publicat a:Sci Rep
Autors principals: Kamata, Hirotoshi, Tsukasaki, Yoshikazu, Sakai, Tsuyoshi, Ikebe, Reiko, Wang, Julia, Jeffers, Ann, Boren, Jake, Owens, Shuzi, Suzuki, Takahiro, Higashihara, Masaaki, Idell, Steven, Tucker, Torry A., Ikebe, Mitsuo
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5496869/
https://ncbi.nlm.nih.gov/pubmed/28676645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-04437-7
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