KIF5A transports collagen vesicles of myofibroblasts during pleural fibrosis

Fibrosis involves the production of extracellular matrix proteins in tissues and is often preceded by injury or trauma. In pleural fibrosis excess collagen deposition results in pleural thickening, increased stiffness and impaired lung function. Myofibroblasts are responsible for increased collagen...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Kamata, Hirotoshi, Tsukasaki, Yoshikazu, Sakai, Tsuyoshi, Ikebe, Reiko, Wang, Julia, Jeffers, Ann, Boren, Jake, Owens, Shuzi, Suzuki, Takahiro, Higashihara, Masaaki, Idell, Steven, Tucker, Torry A., Ikebe, Mitsuo
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2017
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5496869/
https://ncbi.nlm.nih.gov/pubmed/28676645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-04437-7
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