Inhibition of Glycogen Synthase Kinase 3β Blocks Mesomesenchymal Transition and Attenuates Streptococcus pneumonia–Mediated Pleural Injury in Mice

Pleural loculation affects about 30,000 patients annually in the United States and in severe cases can resolve with restrictive lung disease and pleural fibrosis. Pleural mesothelial cells contribute to pleural rind formation by undergoing mesothelial mesenchymal transition (MesoMT), whereby they ac...

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Detalhes bibliográficos
Publicado no:Am J Pathol
Main Authors: Boren, Jake, Shryock, Grant, Fergis, Alexis, Jeffers, Ann, Owens, Shuzi, Qin, Wenyi, Koenig, Kathleen B., Tsukasaki, Yoshikazu, Komatsu, Satoshi, Ikebe, Mitsuo, Idell, Steven, Tucker, Torry A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5809597/
https://ncbi.nlm.nih.gov/pubmed/29073967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2017.07.007
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