Inhibition of Glycogen Synthase Kinase 3β Blocks Mesomesenchymal Transition and Attenuates Streptococcus pneumonia–Mediated Pleural Injury in Mice

Pleural loculation affects about 30,000 patients annually in the United States and in severe cases can resolve with restrictive lung disease and pleural fibrosis. Pleural mesothelial cells contribute to pleural rind formation by undergoing mesothelial mesenchymal transition (MesoMT), whereby they ac...

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發表在:Am J Pathol
Main Authors: Boren, Jake, Shryock, Grant, Fergis, Alexis, Jeffers, Ann, Owens, Shuzi, Qin, Wenyi, Koenig, Kathleen B., Tsukasaki, Yoshikazu, Komatsu, Satoshi, Ikebe, Mitsuo, Idell, Steven, Tucker, Torry A.
格式: Artigo
語言:Inglês
出版: American Society for Investigative Pathology 2017
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5809597/
https://ncbi.nlm.nih.gov/pubmed/29073967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2017.07.007
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