Inhibition of Glycogen Synthase Kinase 3β Blocks Mesomesenchymal Transition and Attenuates Streptococcus pneumonia–Mediated Pleural Injury in Mice

Pleural loculation affects about 30,000 patients annually in the United States and in severe cases can resolve with restrictive lung disease and pleural fibrosis. Pleural mesothelial cells contribute to pleural rind formation by undergoing mesothelial mesenchymal transition (MesoMT), whereby they ac...

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Publicado en:Am J Pathol
Autores principales: Boren, Jake, Shryock, Grant, Fergis, Alexis, Jeffers, Ann, Owens, Shuzi, Qin, Wenyi, Koenig, Kathleen B., Tsukasaki, Yoshikazu, Komatsu, Satoshi, Ikebe, Mitsuo, Idell, Steven, Tucker, Torry A.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Investigative Pathology 2017
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5809597/
https://ncbi.nlm.nih.gov/pubmed/29073967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2017.07.007
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