KIF5A transports collagen vesicles of myofibroblasts during pleural fibrosis

Fibrosis involves the production of extracellular matrix proteins in tissues and is often preceded by injury or trauma. In pleural fibrosis excess collagen deposition results in pleural thickening, increased stiffness and impaired lung function. Myofibroblasts are responsible for increased collagen...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kamata, Hirotoshi, Tsukasaki, Yoshikazu, Sakai, Tsuyoshi, Ikebe, Reiko, Wang, Julia, Jeffers, Ann, Boren, Jake, Owens, Shuzi, Suzuki, Takahiro, Higashihara, Masaaki, Idell, Steven, Tucker, Torry A., Ikebe, Mitsuo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5496869/
https://ncbi.nlm.nih.gov/pubmed/28676645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-04437-7
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