Intrapleural Adenoviral Delivery of Human Plasminogen Activator Inhibitor–1 Exacerbates Tetracycline-Induced Pleural Injury in Rabbits

Elevated concentrations of plasminogen activator inhibitor–1 (PAI-1) are associated with pleural injury, but its effects on pleural organization remain unclear. A method of adenovirus-mediated delivery of genes of interest (expressed under a cytomegalovirus promoter) to rabbit pleura was developed a...

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Detalhes bibliográficos
Main Authors: Karandashova, Sophia, Florova, Galina, Azghani, Ali O., Komissarov, Andrey A., Koenig, Kathy, Tucker, Torry A., Allen, Timothy C., Stewart, Kris, Tvinnereim, Amy, Idell, Steven
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2013
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3547083/
https://ncbi.nlm.nih.gov/pubmed/23002099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2012-0183OC
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