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The mitochondrial anti-viral protein MAVS associates with NLRP3 and regulates its inflammasome activity()

NLRP3 assembles an inflammasome complex that activates caspase-1 upon sensing various danger signals derived from pathogenic infection, tissue damage and environmental toxins. How NLRP3 senses these various stimuli is still poorly understood, but mitochondria and mitochondrial reactive oxygen specie...

詳細記述

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書誌詳細
主要な著者: Park, Sangjun, Juliana, Christine, Hong, Sujeong, Datta, Pinaki, Hwang, Inhwa, Fernandes-Alnemri, Teresa, Yu, Je-Wook, Alnemri, Emad S.
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3848201/
https://ncbi.nlm.nih.gov/pubmed/24048902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301170
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