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Proteome-wide analyses of human hepatocytes during differentiation and dedifferentiation
Failure to predict hepatotoxic drugs in preclinical testing makes it imperative to develop better liver models with a stable phenotype in culture. Stem cell-derived models offer promise, with differentiated hepatocyte-like cells currently considered to be “fetal-like” in their maturity. However, thi...
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Main Authors: | , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
WILEY-VCH Verlag
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3842115/ https://ncbi.nlm.nih.gov/pubmed/23526496 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.26414 |
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