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Lytic Granule Polarization, rather than Degranulation, is the Preferred Target of Inhibitory Receptors in NK Cells()
Natural cytotoxicity is achieved by polarized release of perforin and granzymes at the NK–target cell immunological synapse. Signals for granule polarization and degranulation can be uncoupled in NK cells, which raises the question of their respective sensitivity to inhibitory receptors. Expression...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3842026/ https://ncbi.nlm.nih.gov/pubmed/20833835 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1001220 |
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