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Cytolytic granule polarization and degranulation controlled by different receptors in resting NK cells

The relative contribution to cytotoxicity of each of the multiple NK cell activation receptors has been difficult to assess. Using Drosophila insect cells, which express ligands of human NK cell receptors, we show that target cell lysis by resting NK cells is controlled by different receptor signals...

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Detalhes bibliográficos
Main Authors: Bryceson, Yenan T., March, Michael E., Barber, Domingo F., Ljunggren, Hans-Gustaf, Long, Eric O.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2213171/
https://ncbi.nlm.nih.gov/pubmed/16203869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20051143
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