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Two modes of lytic granule fusion during degranulation by natural killer cells

Lytic granules in cytotoxic lymphocytes, which include T cells and natural killer (NK) cells, are secretory lysosomes that release their content upon fusion with the plasma membrane (PM), a process known as degranulation. Although vesicle exocytosis has been extensively studied in endocrine and neur...

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Detalhes bibliográficos
Main Authors: Liu, Dongfang, Martina, Jose A, Wu, Xufeng S, Hammer III, John A, Long, Eric O
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3257049/
https://ncbi.nlm.nih.gov/pubmed/21483445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/icb.2010.167
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