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Calcineurin dependent lytic granule exocytosis in NK-92 Natural Killer cells

Cytotoxic T cells (CTLs) and natural killer cells (NKs) both kill virus-infected cells and tumor cells by releasing the cytoxic contents of their lytic granules. We recently demonstrated a role for calcineurin in lytic granule exocytosis in TALL-104 human leukemic CTLs[1]. However, whether calcineur...

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Autores principales: Pores-Fernando, Arun T., Gaur, Surabhi, Doyon, Michelle Y., Zweifach, Adam
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2646370/
https://ncbi.nlm.nih.gov/pubmed/18762287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellimm.2008.07.004
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