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ERK activation is only one role of PKC in TCR-independent cytotoxic T cell granule exocytosis
Cytotoxic T cells (CTLs) kill target cells by releasing lytic agents via regulated exocytosis. Three signals are known to be required for exocytosis: an increase in intracellular Ca(2+), activation of protein kinase C (PKC) and activation of extracellular signal regulated signal kinase (ERK). ERK ac...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2491452/ https://ncbi.nlm.nih.gov/pubmed/18413231 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2008.04.028 |
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