ERK activation is only one role of PKC in TCR-independent cytotoxic T cell granule exocytosis

Cytotoxic T cells (CTLs) kill target cells by releasing lytic agents via regulated exocytosis. Three signals are known to be required for exocytosis: an increase in intracellular Ca(2+), activation of protein kinase C (PKC) and activation of extracellular signal regulated signal kinase (ERK). ERK ac...

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Hlavní autoři: Pores-Fernando, Arun T., Gaur, Surabhi, Grybko, Michael J., Zweifach, Adam
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2491452/
https://ncbi.nlm.nih.gov/pubmed/18413231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2008.04.028
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