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Unfolding of a Small Protein Proceeds via Dry and Wet Globules and a Solvated Transition State

Dissecting a protein unfolding process into individual steps can provide valuable information on the forces that maintain the integrity of the folded structure. Solvation of the protein core determines stability, but it is not clear when such solvation occurs during unfolding. In this study, far-UV...

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Bibliografske podrobnosti
Main Authors: Sarkar, Saswata Sankar, Udgaonkar, Jayant B., Krishnamoorthy, Guruswamy
Format: Artigo
Jezik:Inglês
Izdano: The Biophysical Society 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3838737/
https://ncbi.nlm.nih.gov/pubmed/24268151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.09.048
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