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Continuous dissolution of structure during the unfolding of a small protein

The unfolding kinetics of many small proteins appears to be first order, when measured by ensemble-averaging probes such as fluorescence and circular dichroism. For one such protein, monellin, it is shown here that hidden behind this deceptive simplicity is a complexity that becomes evident with the...

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Detalhes bibliográficos
Main Authors: Jha, Santosh Kumar, Dhar, Deepak, Krishnamoorthy, Guruswamy, Udgaonkar, Jayant B.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2708691/
https://ncbi.nlm.nih.gov/pubmed/19553216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0812564106
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