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Thermodynamic Characterization of the Unfolding of the Prion Protein

The prion protein appears to be unusually susceptible to conformational change, and unlike nearly all other proteins, it can easily be made to convert to alternative misfolded conformations. To understand the basis of this structural plasticity, a detailed thermodynamic characterization of two varia...

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Bibliographic Details
Main Authors: Moulick, Roumita, Udgaonkar, Jayant B.
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3907226/
https://ncbi.nlm.nih.gov/pubmed/24461016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.11.4491
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