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Thermodynamic Characterization of the Unfolding of the Prion Protein
The prion protein appears to be unusually susceptible to conformational change, and unlike nearly all other proteins, it can easily be made to convert to alternative misfolded conformations. To understand the basis of this structural plasticity, a detailed thermodynamic characterization of two varia...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The Biophysical Society
2014
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3907226/ https://ncbi.nlm.nih.gov/pubmed/24461016 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.11.4491 |
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