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How cooperative are protein folding and unfolding transitions?

A thermodynamically and kinetically simple picture of protein folding envisages only two states, native (N) and unfolded (U), separated by a single activation free energy barrier, and interconverting by cooperative two‐state transitions. The folding/unfolding transitions of many proteins occur, howe...

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Detalhes bibliográficos
Publicado no:Protein Sci
Main Authors: Malhotra, Pooja, Udgaonkar, Jayant B.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5079258/
https://ncbi.nlm.nih.gov/pubmed/27522064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3015
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