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Dry Molten Globule Intermediates and the Mechanism of Protein Unfolding

New experimental results show that either gain or loss of close packing can be observed as a discrete step in protein folding or unfolding reactions. This finding poses a significant challenge to the conventional two-state model of protein folding. Results of interest involve dry molten globule inte...

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Autors principals: Baldwin, Robert L., Frieden, Carl, Rose, George D.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2927783/
https://ncbi.nlm.nih.gov/pubmed/20635344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.22803
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