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Mast cells suppress murine GVHD in a mechanism independent of CD4(+)CD25(+) regulatory T cells
To investigate the role of mast cells in hematopoietic cell transplantation, we assessed graft-versus-host disease (GVHD) in C57BL/6-Kit(W-sh/W-sh) recipients, which virtually lack mast cells, compared with C57BL/6 WT recipients. GVHD was severely exacerbated in C57BL/6-Kit(W-sh/W-sh) mice (median s...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society of Hematology
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3837515/ https://ncbi.nlm.nih.gov/pubmed/24030387 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-08-519157 |
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