Mast cells suppress murine GVHD in a mechanism independent of CD4(+)CD25(+) regulatory T cells

To investigate the role of mast cells in hematopoietic cell transplantation, we assessed graft-versus-host disease (GVHD) in C57BL/6-Kit(W-sh/W-sh) recipients, which virtually lack mast cells, compared with C57BL/6 WT recipients. GVHD was severely exacerbated in C57BL/6-Kit(W-sh/W-sh) mice (median s...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Leveson-Gower, Dennis B., Sega, Emanuela I., Kalesnikoff, Janet, Florek, Mareike, Pan, Yuqiong, Pierini, Antonio, Galli, Stephen J., Negrin, Robert S.
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2013
Assuntos:
Transplantation
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3837515/
https://ncbi.nlm.nih.gov/pubmed/24030387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-08-519157
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares