Lataa...
Na(+)/H(+) Exchangers Induce Autophagy in Neurons and Inhibit Polyglutamine-Induced Aggregate Formation
In polyglutamine diseases, an abnormally elongated polyglutamine results in protein misfolding and accumulation of intracellular aggregates. Autophagy is a major cellular degradative pathway responsible for eliminating unnecessary proteins, including polyglutamine aggregates. Basal autophagy constit...
Tallennettuna:
| Päätekijät: | , , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Public Library of Science
2013
|
| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3836979/ https://ncbi.nlm.nih.gov/pubmed/24278418 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0081313 |
| Tagit: |
Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!
|