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Inhibition of Protein Misfolding/Aggregation Using Polyglutamine Binding Peptide QBP1 as a Therapy for the Polyglutamine Diseases

Protein misfolding and aggregation in the brain have been recognized to be crucial in the pathogenesis of various neurodegenerative diseases, including Alzheimer’s, Parkinson’s, and the polyglutamine (polyQ) diseases, which are collectively called the “protein misfolding diseases”. In the polyQ dise...

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Hlavní autoři: Popiel, H. Akiko, Takeuchi, Toshihide, Burke, James R., Strittmatter, Warren J., Toda, Tatsushi, Wada, Keiji, Nagai, Yoshitaka
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer US 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3701761/
https://ncbi.nlm.nih.gov/pubmed/23504628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13311-013-0184-7
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