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Inhibition of Protein Misfolding/Aggregation Using Polyglutamine Binding Peptide QBP1 as a Therapy for the Polyglutamine Diseases

Protein misfolding and aggregation in the brain have been recognized to be crucial in the pathogenesis of various neurodegenerative diseases, including Alzheimer’s, Parkinson’s, and the polyglutamine (polyQ) diseases, which are collectively called the “protein misfolding diseases”. In the polyQ dise...

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Bibliografski detalji
Glavni autori: Popiel, H. Akiko, Takeuchi, Toshihide, Burke, James R., Strittmatter, Warren J., Toda, Tatsushi, Wada, Keiji, Nagai, Yoshitaka
Format: Artigo
Jezik:Inglês
Izdano: Springer US 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3701761/
https://ncbi.nlm.nih.gov/pubmed/23504628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13311-013-0184-7
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