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Synthesis of Plantazolicin Analogues Enables Dissection of Ligand Binding Interactions of a Highly Selective Methyltransferase
[Image: see text] A convergent strategy for the synthesis of truncated analogues of plantazolicin (PZN), a member of the thiazole/oxazole-modified microcin (TOMM) class of natural products, has been developed. These N-terminal mono-, tri- and pentazole substructures of PZN were utilized to probe the...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3836752/ https://ncbi.nlm.nih.gov/pubmed/24063702 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol402444a |
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