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Synthesis and Binding Affinity of Homologated Adenosine Analogues as A(3) Adenosine Receptor Ligands
Homologated analogues 3a and 3b of potent and selective A(3) adenosine receptor ligands, IB-MECA and dimethyl-IB-MECA were synthesized from commercially available 1-O-acetyl-2,3,5-tri-O-benzoyl-β-d-ribofuranose (4) via Co(2)(CO)(8)-catalyzed siloxymethylation as a key step. Unfortunately, homologate...
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| Publicado no: | Bull Korean Chem Soc |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4478603/ https://ncbi.nlm.nih.gov/pubmed/26120223 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5012/bkcs.2011.32.5.1620 |
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