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Structural and functional insight into an unexpectedly selective N-methyltransferase involved in plantazolicin biosynthesis
Plantazolicin (PZN), a polyheterocyclic, N(α),N(α)-dimethylarginine–containing antibiotic, harbors remarkably specific bactericidal activity toward strains of Bacillus anthracis, the causative agent of anthrax. Previous studies demonstrated that genetic deletion of the S-adenosyl-l-methionine–depend...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3740862/ https://ncbi.nlm.nih.gov/pubmed/23878226 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1306101110 |
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