Structural and functional insight into an unexpectedly selective N-methyltransferase involved in plantazolicin biosynthesis

Plantazolicin (PZN), a polyheterocyclic, N(α),N(α)-dimethylarginine–containing antibiotic, harbors remarkably specific bactericidal activity toward strains of Bacillus anthracis, the causative agent of anthrax. Previous studies demonstrated that genetic deletion of the S-adenosyl-l-methionine–depend...

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Detaylı Bibliyografya
Asıl Yazarlar: Lee, Jaeheon, Hao, Yue, Blair, Patricia M., Melby, Joel O., Agarwal, Vinayak, Burkhart, Brandon J., Nair, Satish K., Mitchell, Douglas A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2013
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3740862/
https://ncbi.nlm.nih.gov/pubmed/23878226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1306101110
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